Tamiflu ® (oseltamivir phosphate) is the first oral antiviral that is used for therapy and prevention of influenza. Tamiflu entry in the group of drugs known as neuraminidase resistor (neuraminidase inhibitors - NAIs). NAIs designed to specifically attack memcegah virus and influenza virus replication in the body with one of the two surfaces of the structure of the influenza virus neuraminidase protein.
Neuraminidase enables the virus to continue to menginfeksi cells' employer '. If neuraminidase dihambat, the virus will not be able to exit from the cells' employer 'and die, so that the virus can not spread menginfeksi and other cells in the body. Unlike the old antivirus, resistor M2, NAIs effective against influenza virus types A and B.
Tamiflu is available for influenza therapy in adults and children over 1 year. More than 33 million patients have been diterapi with Tamiflu in more than 60 countries including the United States, Japan, Canada, Australia, European Union, Switzerland, Latin America and Indonesia. Tamiflu is also dietujui in the European Union and the United States for the prevention of influenza in adolescents over 13 years.
In case of pandemic, World Health Organization (WHO) estimates the necessary time to six months to isolate and produce vaccines that are appropriate for the type of virus that caused a pandemic 14. Suit a period of six months, as long as vaccine is being developed, anti-virus has a role in the early phases of pandemic. Tamiflu has been tested by the WHO against various types of influenza virus and has been proven effective against the type of virus inluenza H7 and H9. Data also show that Tamiflu effective against bird flu virus type H5N1 is 15 at this time be in the middle of Southeast Asia.
Provision of anti virus such as Tamiflu has been recommended by the UN (or WHO?) Since 1999 as part of the "Pandemic Preparedness Plan" 16, which was developed to assist the government in preparation for their pandemic.
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